Below are recently opened clinical trials that are currently available at Fox Chase Cancer Center. To refer a patient to any of these studies, please call 215-214-1515 or visit FoxChase.org/ClinicalTrials.
Featured Clinical Trials
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The investigators hypothesize that Scrambler therapy with duloxetine, compared to duloxetine-based usual care, will result in greater improvement in CIPN as measured by the BPI-Short Form.
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This phase II trial tests the effect of hemp-based cannabidiol (CBD) in preventing oxaliplatin (Ox)-induced peripheral neuropathy (OIPN) in patients with colorectal cancer (CRC) that has spread to nearby tissue or lymph nodes and cannot ...
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This is a single-arm, open-label, non-randomized Phase II trial evaluating the efficacy of induction therapy with enfortumab vedotin (EV) plus pembrolizumab (P) for 18 weeks (6 cycles), followed by maintenance pembrolizumab in treatment-naïve ...
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Dose-Attenuated Chemotherapy in Patients with Lung Cancer and Age >/= 70 and/or Comorbidities
This is an open-label, non-randomized, single-center, phase II study to evaluate the efficacy, toxicity and, tolerability of pre-specified dose attenuated chemotherapy regimens in lung cancer patients with comorbidities.
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In this study, we will use an innovative approach called Adaptive Radiation Therapy (ART). ART factors in the internal anatomical changes. Recent advancements in radiation technology now permit taking a Cone Beam CT (CBCT) scan before ...
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The purpose of this study is to demonstrate that adaptive radiotherapy for locally advanced cervical cancer will translate into a decreased rate of acute gastrointestinal toxicity compared with the historically reported rate for non-adaptive ...
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Adaptive Radiation for Abdominopelvic Metastases (ARAM) - Clinical Trial
Recent advancements in radiation technology permit daily adjustment of the radiation plan to account for changes in position of the organs in your abdomen and pelvis and variations in the surrounding normal tissues. This means a new radiation ...
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The purpose of the study is to evaluate the safety and effectiveness of the GORE® Tissue Reinforcement for Breast Reconstruction (TRBR) Device. This investigational device is designed to support soft tissue during two-stage, implant-based ...
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This trial aims at investigating the diagnostic ability of a combined diagnostic panel including systematic endoscopic evaluation (SEE), blood-based ctDNA assay, and urine-based cfDNA assay to predict the presence of residual tumor remaining ...
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The purpose of this study is to compare the usual treatment alone to using hepatic artery infusion chemotherapy plus the usual treatment. The addition of hepatic artery infusion chemotherapy to the usual treatment could shrink your cancer ...
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Iadademstat can be safely combined with approved treatment paclitaxel for relapsed or refractory small cell lung cancer and extrapulmonary high grade neuroendocrine cancer patients whose cancer is no longer responding to initial chemotherapy.
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These hyper-proliferative myeloid malignancies are associated with the mutations in JAK2, CALR, and MPL genes. Current treatment options for these diseases include cyto-reductive therapy with hydroxyurea and the JAK2 inhibitors. Although ...
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The purpose of this research study is to investigate alternative dosing schedules for the drug cabozantinib. Cabozantinib is a drug with FDA approval for metastatic renal cell carcinoma, but is not approved for the treatment of neuroendocrine ...
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To evaluate safety and tolerability of treatment with ACTengine® IMA203/IMA203CD8 products as monotherapy or in combination with nivolumab
